BIOSIMILARS

BIOSIMILARS:What is it…..???

Eyes are one of the most important sensory organs & a beautifully designed biological system. Although it seems to be the most privileged organ , yet it is as invincible as well to make it completely accessible. Ocular therapeutics had been always a challenge for the ophtholmologist and pharmacologist. Moving onward from eye drops to ointments we have covered a long path of innovations  & ocular drug delivery, now reached  to biologics & gene delivery.

Biologics gave a new hope to targeted drug delivery based on the motive of minimising the toxicity and maximising the therapeutic efficacy. But it proved to be a cumbersome , expensive and time taking process.

Now with the latest concept of biosimilars ,it surpassed the idea of biologics as the name suggest they are exactly similar to biologics but comparatively inexpensive and less time consuming in R & D. These are the pros of the biosimilars but nothing comes without cons. Difficulties of manufacturing   biosimilars are that these are large molecules compared to generics like generics biologics don’t have fixed chemical formula .Its an expensive affair to develop biosimilar compared to generics. But still it proved convenient and profitable than biologics development.

Reditux was the biosimilar introduced by Dr.Reddys laboratory Razumab is biosimilar of Ranibizumab developed by Intas pharmaceuticals is doing well in India. It is used for ocular degenerative diseases like wet AMD, Choroidal neovascularisation (CNV) & Diabetic  retinopathy etc. Biosimilars gave a new horizon to ocular drug delivery.

By – ASSISTANT PROFESSOR – : Deepti M Sati
Department – Dept. of Pharmacology
UCBMSH Magazine – (YouthRainBow)
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