Gout is the form of arthritis which is characterised by severe pain, redness and tenderness in joints usually the big toe or fingers, wrists, elbow or knees. Gout is caused by an excess of uric acid in the blood or hyperuricemia. The normal concentration of uric acid in the serum of adults is in the range of 3-7mg/dl. In the women, it is slightly lower than in men. More than 10 million cases per year, mostly affecting males. The signs and symptoms of gout almost always occurs suddenly and often at night. At one time it was thought that gout was caused simply by overeating or drinking too much alcohol. But there are some other risk factors too like age and gender, genetics, lifestyle choices, medications, weight, health problems, such as blood pressure, diabetes etc. Sodium urate crystals get deposited in the soft tissues particularly in the joints known as tophi which is responsible for painful gouty arthritis. The most reliable method to diagnose gout is to measure the level of uric acid in blood or joint fluid test. The majority of gout cases can be treated by using non steroidal anti inflammatory drugs (NSAIDS) colchicines or corticosteroids. Besides the drug therapy, dietary restriction and consumption of plenty of water will also be useful.

By -ASSOCIATE PROFESSOR – Mrs. Deepanjeet Kaur
Department – Biochemistry
UCBMSH Magazine – (YouthRainBow)
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