Bovine mastitis is an infectious disease of the mammary glands of dairy cattle such as cows. It is worldwide in distribution and causes economic loss to the dairy handlers. This disease is mainly caused by coagulase negative bacteria such as Streptococcus agalactiae, Staphylococc us aureus and others bacteria which retained on the teat of cow i.e. E. coli, Streptococcus uberis. These bacteria mainly enter s the mammary glands of cow through their teat canal, where they colonize, proliferate, release toxin and damage the mammary glands cell. After proliferation an increase in Lactose dehydrogenase (LDH) activity shows the infections and also the somatic cell, inflammatory cytokinen.
Bovine mastitis is detected by California mastitis method, which is used as a preliminary detection test and cost effective. Bovine mastitis is treated by intramammary infusion of ointments by intramuscularly/ intravenously and by suitable antibiotics such as steptomycin, ampicillin, Penicillin.