Sjogren’s Syndrome

Sjogren’s Syndrome

Sjogren’s pronounced as ‘SHOW Grins ‘ syndrome is an auto immune disease .Auto immune disease refers to disorder in our own immune system doesn’t recognize our own body tissue and endogenous compound and treat it as an antigen and obviously if it is treating like antigen,it will try to kill or neutralize it and eliminate from body .This is what very unfortunate with the auto immune disease and make them difficult and almost impossible to treat.That is the reason in most of the autoimmune disorders Clinicians can just provide symptomatic relief can’t provide the cure or complete treatment.

Sjogren’s syndrome was named after the Swedish physician Dr.Henrik Sjogren who first identified this disease in 1933. Major symptoms involve dryness of eyes and mouth. It also dryness of other organs like liver, kidney etc.Along with it patients feel fatigue and exhausted leading to permanent impairment and affect the quality of life. As it lead to tooth decay ,difficulty in speaking swallowing, persistent dry cough etc.If symptoms of Sjogren’s syndrome appear along with other Auto immune disease like SLE(Systemic Lupus Erythromatosus) or Rheumatoid Arthritis . It is known as Secondary Sjogren’s Syndrome.

Etiology of Sjogren’s Syndrome is still mystery to scientists that why only in few people develop this syndrome. It has been postulated to be associated with genetics like if a person develop this syndrome chances of his or her relative to get the syndrome are enhanced.Research finding also add that to develop such syndrome immune system also need to be activated or stimulated by some bacterial or viral infection.Studies indicated that females are more prone to it compared to males.
Treatment aims at providing relief from the symptoms :
1.Dry eye :Ocular lubricants eye drops ,Autologous serum for severe cases
2.Dry Mouth: Secretagogue like Pilocarpine increase saliva
3.Dry throat :Medication which increase moisture like sorbitol etc
4. Joint Pain: NSAID’s (Nonsteroidal Anti inflammatory drugs)& DMARD(Disease modifying anti rheumatic drugs)

By – Assistant Professor – Ms. DEEPTI M SATI
Department – Pharmacology
UCBMSH Magazine – (YouthRainBow)
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